How CPK Test Can Help Diagnose Muscle Disorders


There are many types of enzymes in our body, and creatine phosphokinase CPK enzyme is an important one in the body. Enzymes play an important role in the metabolic functions and biochemical functions of the body. Therefore, the fluctuations in these enzyme levels have a strong connection with our body vitals. The enzyme CPK is also a metabolic indicator and has many functions. The CPK enzyme is important for the proper functioning of body muscles. The CPK test checks for the levels of CPK in your body and is accompanied by other tests. The CPK enzyme is related to certain parts of the body, and its presence in the bloodstream can show the level of damage to certain internal organs.

Where is CPK produced?

The CPK enzyme is produced in the brain and lungs of a person. The enzyme’s variant is also found in the heart and the skeletal muscles. When these parts are damaged or injured, they release CPK into the bloodstream, and the level of CPK goes up. The enzyme and its isozyme can help detect damage in our internal organs so that the doctor can decide on the right treatment approach.

The CPK test is done for the following reasons.

  • Diagnosis of heart attack– Often, the patient might undergo a heart attack and might not know the extent of the attack or its severity. The severity of the heart attack and damage caused by it is diagnosed with a CPK test
  • Diagnosis of chest pain– The patient might come in with a complaint of chest pain. Chest pain can happen because of many reasons, like heartburn and acidity. However, a proper diagnosis of chest pain can help in taking precautionary measures against future heart attacks
  • Muscle damage diagnosis-After physical trauma and accidents, muscle injury, and damage, are very common. Even after recovering from an accident, the damage might be extensive. In such cases, a CPK test is necessary
  • Muscle disease and disorders– Many complex muscle diseases and disorders can be diagnosed with the help of a CPK test. Polymyositis and dermatomyositis can be checked with the help of a CPK test
  • Muscle breakdown due to over-exercising can also be diagnosed and monitored with a CPK test

Preparation for CPK test

CPK test is not difficult and is the same as any other blood sample test. The patient does not have to worry or take precautions before a CPK test. The patient does not have to fast or follow any special rules. However, the doctor might ask you about any type of OTC or prescribed medications before the test. Medications like cholesterol-controlling drugs and steroids are stopped before a test.

Process of the CPK test

The process of a CPK test is simple and starts with blood sample collection. A phlebotomist or doctor will collect the sample from your arm with an intravenous syringe. The blood sample is collected and sent to the lab for analysis. The doctor might also suggest a whole blood panel test apart from the CPK test. There are no major risks linked with a CPK test. The use of a sterile syringe and a good bandage help avoid any infections later.

The results of the CPK test

A CPK test usually costs about Rs 200-300 and comes with other blood sample tests. The CPK test results are different for different isozymes. A major brain injury due to stroke or bleeding can be a reason for a high level of CPK 1 in your blood. If you have been experiencing frequent seizures, it is advisable to go for a CPK 1 test. The high level of CPK 1 also shows the possibility of brain cancer and damage to the pulmonary system.

CPK 2 levels go up when there is damage to the roots from a heart attack. Injury or inflammation of the heart can cause high levels of CPK 2 enzyme. The CPK test also monitors the heart recovery rate after open-heart surgery. CPK 3 levels have a strong link with the skeletal muscles and their health. Monitoring the CPK 3 levels diagnoses muscular injuries and damage. Conditions like muscular dystrophy, seizures, and muscle trauma are checked and monitored with the help of CPK 3 tests. The CPK test is important for knowing and locating the site of injury after trauma. During the recovery process, the CPK test is necessary for monitoring the recovery pace and the damage level. High levels of CPK show that you have suffered damage to your muscles recently. The isozyme tests help locate the issue and target treatment in a proper way. However, to know the full extent of the damage, a doctor may suggest other tests.

Read: How Online PCOS Tests Can Help Diagnose the Condition?

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